Based on Shakespeare's play manuscripts, he was the first known user of the following words.  Click on the underlined words to see the OED definition and etymology.

Accused (n.)

Dickens (n.)

Green-eyed (adj.)

Misquote (v.)

Scuffle (n.)

Addiction (n.)

Discontent (n.)

Grovel (v.)

Monumental (adj.)

Seamy side (n.)

Aerial (adj.)

Disgraceful (adj.)

Gust (n.)

Moonbeam (n.)

Secure (v.)

Alligator (n.)

Dislocate (v.)

High-pitched (adj.)

Mountaineer (n.)

Shooting star (n.)

Amazement (n.)

Divest (v.)

Hint (n.)

Negotiate (v.)

Shudder (n.)

Anchovy (n.)

Domineering (adj.)

Hobnob (v.)

Never-ending (adj.)

Softhearted (adj.)

Arouse (v.)

Downstairs (adv.)

Humor (v.)

New-fallen (adj.)

Splitting (adj.)

Assassination (n.)

Drug (v.)

Hurry (v.)

Noiseless (adj.)

Stealthy (adj.)

Auspicious (adj.)

Dwindle (v.)

Hush (adj.)

Numb (v.)

Submerge (v.)

Backing (n.)

Elbow (v.)

Immediacy (n.)

Obscene (adj.)

Swagger (v.)

Bandit (n.)

Embrace (n.)

Impede (v.)

Ode (n.)

Tardiness (n.)

Baseless (adj.)

Employer (n.)

Importantly (adv.)

Outbreak (n.)

Threateningly (adv.)

Be-all and end-all (n.)

Engagement (n.)

Inaudible (adj.)

Pageantry (n.)

Tightly (adv.)

Bedroom (n.)

Enmesh (v.)

Instinctively (adv.)

Pander (v.)

Torture (v.)

Besmirch (v.)

Epileptic (adj.)

Investment (n.)

Partner (v.)

Traditional (adj.)

Bet (v.)

Equivocal (Adj.)

(In)vulnerable (adj.)

Pedant (n.)

Tranquil (adj.)

Birthplace (n.)

Eventful (adj.)

Jaded (adj.)

Perusal (n.)

Transcendence (n.)

Blanket (v.)

Excitement (n.)

Jet (v.)

Petition (v.)

Unclog (v.)

Bloodstained (adj.)

Exposure (n.)

Label (v.)

Premeditated (adj.)

Undervalue (v.)

Blushing (adj.)

Eyeball (n.)

Lackluster (adj.)

Promethean (adj.)

Undress (v.)

Bump (n.)

Farmhouse (n.)

Lapse (v.)

Puke (v.)

Unmitigated (adj.)

Buzzer (n.)

Fashionable (adj.)

Laughable (adj.)

Quarrelsome (adj.)

Unreal (adj.)

Cake (v.)

Fixture (n.)

Launder (v.)

Questioning (n.)

Urging (n.)

Cater (v.)

Flawed (adj.)

Leapfrog (n.)

Radiance (n.)

Varied (adj.)

Champion (v.)

Foregone (adj.)

Lonely (adj.)

Rancorous (adj.)

Vastly (adv.)

Circumstantial (adj.)

Fortune-teller (n.)

Love letter (n.)

Rant (v.)/ Ranting (adj.)

Vaulting (adj.)

Cold-blooded (adj.)

Forward (v.)

Lower (v.)

Reclusive (adj.)

Watchdog (n.)

Compromise (v.)

Frugal (adj.)

Luggage (n.)

Reinforcement (n.)

Well-behaved (adj.)

Courtship (n.)

Full-grown (adj.)

Lustrous (adj.)

Remorseless (adj.)

Widen (v.)

Critic (n.)

Generous (adj.)

Madcap (adj.)

Retirement (n.)

Widowed (adj.)

Dauntless (adj.)

Gloomy (adj.)

Majestic (adj.)

Reword (v.)

Wild-goose chase (n.)

Dawn (n.)

Glow (n.)

Manager (n.)

Rival (adj./v.)

Wormhole (n.)

Deafening (adj.)

Gnarled (adj.)

Marketable (adj.)

Sacrificial (adj.)

Worthless (adj.)

Denote (v.)

Go-between (n.)

Mimic (n.)

Sanctimonious (adj.)

Yelping (adj.)

Design (n.)

Gossip (v.)

Misgiving (n.)

Savagery (n.)

Zany (n.)